Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 13/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 13/20 | 0.43 |
| ▸ | GBA1 | P04062 | 12/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.37 |
| ▸ | LCT | P09848 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31163911 | 0.91 | UGCG (0.37) | UGCGGBA2GBA1SILCT | |
| SCHEMBL31163908 | 0.90 | UGCG (0.39) | UGCGGBA2GBA1SILMNA | |
| SCHEMBL31163903 | 0.88 | UGCG (0.53) | UGCGGBA2GBA1SILMNA | |
| SCHEMBL31163825 | 0.88 | UGCG (0.53) | UGCGGBA2GBA1SILMNA | |
| SCHEMBL31163902 | 0.85 | UGCG (0.36) | UGCGGBA2GBA1SILCT | |
| SCHEMBL31163893 | 0.82 | LMNA (0.41) | UGCGGBA2GBA1LMNANTMT1 | |
| Hydrochloric Acid SCHEMBL31163778 | 0.80 | UGCG (0.55) | UGCGGBA2GBA1SILCT | |
| SCHEMBL31163890 | 0.80 | SHMT2 (0.43) | UGCGGBA2GBA1SILCT | |
| SCHEMBL31163682 | 0.79 | GBA1 (0.39) | UGCGGBA2GBA1LMNANTMT1 | |
| SCHEMBL31163846 | 0.78 | UGCG (0.53) | UGCGGBA2GBA1SILMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024179491-A1 | GBA1 AND GCS DUAL MODULATOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-09-06 | — | — | WO | disclosed |