Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 2/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049916 | 0.95 | JAK2 (0.37) | JAK2JAK1BTK | |
| SCHEMBL31622408 | 0.90 | JAK2 (0.32) | JAK2JAK1 | |
| SCHEMBL30686997 | 0.85 | JAK2 (0.30) | JAK2JAK1 | |
| SCHEMBL30639342 | 0.79 | LATS1 (0.32) | LATS1LATS2 | |
| SCHEMBL30639341 | 0.79 | LATS1 (0.32) | LATS1LATS2 | |
| SCHEMBL31571836 | 0.79 | LATS1 (0.32) | LATS1LATS2 | |
| SCHEMBL14734142 | 0.79 | LATS1 (0.32) | LATS1LATS2 | |
| SCHEMBL30758491 | 0.77 | LATS1 (0.30) | LATS1LATS2 | |
| SCHEMBL14754619 | 0.77 | LATS1 (0.31) | LATS1LATS2 | |
| SCHEMBL29576569 | 0.76 | LATS1 (0.32) | JAK2JAK1LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596554-A1 | AZA-FUSED RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | Suzhou Arkbiopharmaceutical Co., Ltd. (CN) | 2025-08-06 | — | — | EP | disclosed |
| CN-119930644-A | Phosphodiesterase 4B inhibitor and preparation method and application thereof | 合肥医工医药股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024213089-A1 | SUBSTITUTED DIHYDROTHIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海壹迪生物技术有限公司 | 2024-10-17 | — | — | WO | disclosed |
| WO-2024208225-A1 | DIHYDROTHIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海壹迪生物技术有限公司 | 2024-10-10 | — | — | WO | disclosed |