Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25388469 | 0.81 | LTA4H (0.40) | PDGFRBPDGFRALTA4HRAB9AMAPK14 | |
| SCHEMBL31166963 | 0.78 | ALOX5 (0.50) | MAOBLTA4HMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL10253764 | 0.76 | P4HTM (0.51) | MAOBLTA4HMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL31166788 | 0.76 | MAOB (0.50) | PDGFRBPDGFRAMAOBLTA4HMAPT | |
| SCHEMBL12392129 | 0.76 | P4HTM (0.51) | MAOBLTA4HMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL31167021 | 0.75 | PDGFRB (0.41) | PDGFRBPDGFRAMAOBMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2140034 | 0.75 | P4HTM (0.50) | MAOBLTA4HMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL18865248 | 0.72 | MAOB (0.54) | PDGFRBPDGFRAMAOBMAPTL3MBTL1 | |
| SCHEMBL28563970 | 0.72 | HTT (0.49) | PDGFRBPDGFRALTA4HMAPTL3MBTL1 | |
| SCHEMBL20067907 | 0.72 | HTT (0.49) | PDGFRBPDGFRALTA4HMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698520-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | Gandeeva Therapeutics, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220708-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | GANDEEVA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |