SCHEMBL3116754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1966212	0.84	ERBB2 (0.53)	ERBB2HSP90AA1HSP90AB1DHFREGFR
	SCHEMBL3740870	0.78	ERBB2 (0.43)	ERBB2HSP90AA1HSP90AB1DHFREGFR
	SCHEMBL14467034	0.77	ERBB2 (0.41)	ERBB2HSP90AA1HSP90AB1DHFRMAP4K4
	SCHEMBL3111577	0.77	HSP90B1 (0.50)	ERBB2HSP90AA1HSP90AB1DHFREGFR
	SCHEMBL3127628	0.77	ERBB2 (0.41)	ERBB2MEN1KMT2AHSP90AA1HSP90AB1
	SCHEMBL3128953	0.76	ERBB2 (0.40)	ERBB2HSP90AA1HSP90AB1DHFREGFR
	SCHEMBL4339904	0.76	ERBB2 (0.52)	ERBB2HSP90AA1HSP90AB1MAP4K4
	SCHEMBL3126758	0.76	HSP90AB1 (0.51)	ERBB2HSP90AA1HSP90AB1MAP4K4
	SCHEMBL13079975	0.76	GAA (0.41)	ERBB2NPC1MEN1KMT2AHSP90AA1
	SCHEMBL14384475	0.74	ENPP1 (0.43)	ERBB2HSP90AA1HSP90AB1DHFRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.