Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31167557 | 1.00 | HPGD (0.44) | HPGDAAK1ALDH1A1GAAMEN1 | |
| SCHEMBL406327 | 0.88 | HPGD (0.47) | HPGDAAK1ALDH1A1GAAMEN1 | |
| SCHEMBL29649018 | 0.85 | NLRP3 (0.55) | HPGDAAK1ALDH1A1GAARAB9A | |
| SCHEMBL23750713 | 0.85 | AAK1 (0.56) | AAK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL22987921 | 0.85 | NLRP3 (0.55) | HPGDAAK1ALDH1A1GAARAB9A | |
| SCHEMBL28485544 | 0.84 | ALDH1A1 (0.50) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL404755 | 0.84 | HPGD (0.64) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL404741 | 0.81 | POLB (0.44) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL405736 | 0.81 | ALDH1A1 (0.55) | HPGDALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4298397 | 0.81 | ALDH1A1 (0.50) | HPGDALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240086-A1 | COMPOUND FOR REGULATING AND CONTROLLING 15-PGDH ACTIVITY AND PREPARATION METHOD THEREFOR | 成都倍特药业股份有限公司 | 2024-11-28 | — | — | WO | disclosed |