Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25383808 | 0.97 | EPHX2 (0.41) | EPHX2HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL15092031 | 0.79 | HTT (0.61) | EPHX2HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL27309277 | 0.75 | KMT2A (0.66) | EPHX2HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL12787263 | 0.74 | HTT (0.50) | EPHX2HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL16563206 | 0.74 | HSD11B1 (0.47) | EPHX2KMT2AEPHX1CTSLCTSS | |
| SCHEMBL14062633 | 0.72 | HTT (0.44) | EPHX2HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL4630575 | 0.71 | HTR2C (0.62) | EPHX2HTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL10339425 | 0.70 | EPHX2 (0.57) | EPHX2KMT2AFAAH | |
| SCHEMBL23493346 | 0.70 | EPHX2 (0.57) | EPHX2KMT2AL3MBTL1FAAH | |
| SCHEMBL14062631 | 0.70 | HTT (0.42) | EPHX2HTTKMT2ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118871422-A | 3-Alkynyl carboxamides as AEP modulators | 豪夫迈·罗氏有限公司 | 2024-10-29 | — | — | CN | disclosed |