Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23578021 | 0.88 | ABCG2 (0.45) | ABCG2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29909003 | 0.88 | ABCG2 (0.45) | ABCG2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29909184 | 0.87 | ABCG2 (0.52) | ABCG2MAPTALDH1A1GSK3BDHODH | |
| SCHEMBL23576737 | 0.87 | ABCG2 (0.52) | ABCG2MAPTALDH1A1GSK3BDHODH | |
| SCHEMBL29909490 | 0.86 | ABCG2 (0.44) | ABCG2ALDH1A1SMN1; SMN2DHODH | |
| SCHEMBL23576891 | 0.86 | ABCG2 (0.44) | ABCG2ALDH1A1SMN1; SMN2DHODH | |
| SCHEMBL24721427 | 0.85 | ABCG2 (0.41) | ABCG2MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL29909355 | 0.85 | ABCG2 (0.41) | ABCG2MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL23577259 | 0.84 | ABCG2 (0.43) | ABCG2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29909220 | 0.84 | ABCG2 (0.43) | ABCG2MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |