Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1757050 | 0.86 | KDM4E (0.38) | CA12CA2PTPN2PTPN1PTPN5 | |
| SCHEMBL8868764 | 0.85 | MAPT (0.42) | CA12CA2PTPN2PTPN1PTPN5 | |
| SCHEMBL7251612 | 0.84 | GAA (0.46) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL5459757 | 0.83 | ALDH1A1 (0.42) | CA12CA2PTPN2PTPN1PTPN5 | |
| Iodide SCHEMBL4956536 | 0.83 | GAA (0.45) | L3MBTL1MEN1KMT2APOLBMAPT | |
| SCHEMBL10424501 | 0.81 | TP53 (0.47) | CA12CA2L3MBTL1MEN1KMT2A | |
| Biphenyl SCHEMBL23364905 | 0.73 | CA12 (0.49) | CA12CA2L3MBTL1MEN1KMT2A | |
| SCHEMBL9786188 | 0.70 | KMT2A (0.67) | CA12CA2PTPN2PTPN1PTPN5 | |
| SCHEMBL14985579 | 0.70 | SNCA (0.36) | CA12CA2KMT2AMAPTGAA | |
| SCHEMBL1833906 | 0.69 | KDM4E (0.41) | CA12L3MBTL1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4428201-A1 | NEW INFRARED ABSORBERS | European Central Bank (DE) | 2024-09-11 | — | — | EP | disclosed |