Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481019 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL31169578 | 0.83 | CA12 (0.38) | ALDH1A1KDM4ENPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL1833906 | 0.82 | KDM4E (0.41) | ALDH1A1KDM4ENPSR1RXFP1SMN1; SMN2 | |
| Iodide SCHEMBL1874401 | 0.79 | PTPN1 (0.35) | ALDH1A1KDM4ELMNACYP3A4CYP2D6 | |
| SCHEMBL10424501 | 0.78 | TP53 (0.47) | ALDH1A1KDM4ESMN1; SMN2HPGDGAA | |
| SCHEMBL7491820 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4ENPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL7491818 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4ENPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL1656260 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KDM4ENPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL3396649 | 0.74 | KDM4E (0.41) | ALDH1A1KDM4ENPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL3180420 | 0.73 | GAA (0.62) | ALDH1A1KDM4ESMN1; SMN2PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | Terpetschnig, Ewald (US) | 2007-12-06 | — | — | US | disclosed |
| US-6143434-A | HIGH LUMINANCE AND A HIGH LUMINESCENT EFFICIENCY AT A LOW DRIVING VOLTAGE AND HAS EXCELLENT STABILITY IN REPETITIONS OF USE | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | SPR, SRRT, SQLE | ALDH1A1 2350/4885KDM4E 2948/4885NPSR1 2668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.