Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12750810 | 0.78 | KDM4A (0.42) | KDM4AKDM4CKISS1RTSHRLMNA | |
| Hydrochloric Acid SCHEMBL25170217 | 0.77 | KDM4A (0.45) | KDM4AKDM4CKISS1RTSHRLMNA | |
| SCHEMBL6922184 | 0.77 | CES2 (0.45) | TSHR | |
| SCHEMBL6925793 | 0.77 | CES2 (0.45) | TSHR | |
| SCHEMBL6927000 | 0.77 | CES2 (0.45) | TSHR | |
| SCHEMBL6927604 | 0.77 | CES2 (0.45) | TSHR | |
| SCHEMBL31170324 | 0.76 | KDM4A (0.43) | KDM4AKDM4CKISS1RLMNA | |
| SCHEMBL31170662 | 0.73 | KDM4C (0.41) | KDM4AKDM4CKISS1RLMNA | |
| SCHEMBL408247 | 0.73 | ALDH1A1 (0.56) | KDM4AKDM4CKISS1RLMNA | |
| SCHEMBL31170679 | 0.70 | KDM4A (0.39) | KDM4AKDM4CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238633-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-11-21 | — | — | WO | disclosed |