Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 5/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | CDC25A | P30304 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28687446 | 1.00 | ALDH1A1 (0.42) | ALDH1A1POLBMAPTPPARAPPARG | |
| SCHEMBL22425985 | 0.86 | PPARA (0.37) | PPARAPPARGCTSSJAK2PTPN2 | |
| SCHEMBL22411784 | 0.86 | PPARA (0.37) | PPARAPPARGCTSSJAK2PTPN2 | |
| SCHEMBL28665586 | 0.83 | PPARA (0.35) | PPARAPPARGCTSSGSTP1GSTM2 | |
| SCHEMBL29684374 | 0.83 | PPARA (0.35) | PPARAPPARGCTSSGSTP1GSTM2 | |
| SCHEMBL28687444 | 0.82 | ALDH1A1 (0.43) | ALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL22411916 | 0.78 | PPARA (0.37) | ALDH1A1PPARAPPARGCTSSGSTP1 | |
| SCHEMBL22411915 | 0.78 | PPARA (0.37) | ALDH1A1PPARAPPARGCTSSGSTP1 | |
| SCHEMBL22412052 | 0.78 | MAPT (0.46) | ALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL22412054 | 0.78 | MAPT (0.46) | ALDH1A1POLBMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811534-B | TYK2 inhibitors and uses thereof | 阿鲁米斯公司 | 2024-10-29 | — | — | CN | disclosed |