Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 5/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684374 | 1.00 | PPARA (0.35) | PPARACREBBPPPARGCTSSGSTP1 | |
| SCHEMBL22411874 | 0.88 | CREBBP (0.37) | CREBBPGAAMEN1KMT2A | |
| SCHEMBL28687446 | 0.83 | ALDH1A1 (0.42) | PPARAPPARGCTSSGSTP1GSTM2 | |
| SCHEMBL31172085 | 0.83 | ALDH1A1 (0.42) | PPARAPPARGCTSSGSTP1GSTM2 | |
| SCHEMBL28665584 | 0.83 | CREBBP (0.35) | CREBBPGAAMEN1KMT2A | |
| SCHEMBL31681403 | 0.79 | — | — | |
| SCHEMBL22411929 | 0.79 | — | — | |
| SCHEMBL22412042 | 0.79 | CREBBP (0.36) | CREBBPGAAMEN1KMT2A | |
| SCHEMBL22412040 | 0.79 | CREBBP (0.36) | CREBBPGAAMEN1KMT2A | |
| SCHEMBL31172072 | 0.79 | CREBBP (0.36) | CREBBPGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811534-A | TYK2 inhibitors and uses thereof | 埃斯克疗法股份有限公司 | 2021-12-17 | — | — | CN | disclosed |