Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539892 | 0.74 | SLC6A2 (0.42) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27705364 | 0.72 | SIGMAR1 (0.53) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8101234 | 0.72 | SIGMAR1 (0.53) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1738860 | 0.72 | SIGMAR1 (0.53) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2080509 | 0.72 | SIGMAR1 (0.53) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL104186 | 0.71 | SIGMAR1 (0.51) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL104187 | 0.71 | SIGMAR1 (0.51) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1934350 | 0.71 | SIGMAR1 (0.51) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL104699 | 0.71 | SIGMAR1 (0.51) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27814773 | 0.71 | SIGMAR1 (0.56) | SIGMAR1CYP2C19SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250339570-A1 | RADIOIMMUNOCONJUGATES AND THERAPEUTIC USES THEREOF | UNIV CALIFORNIA (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250127943-A1 | METHODS AND COMPOSITIONS FOR TARGETING DISEASE RELATED CELL SURFACE RECEPTORS USING RADIOLABELED AND/OR CYTOTOXIN LABELLED ANTIBODIES | UNIVERSITY OF SASKATCHEWAN (CA) | 2025-04-24 | — | — | US | disclosed |
| US-12151004-B2 | Methods and compositions for targeting disease related cell surface receptors using radiolabeled and/or cytotoxin labelled antibodies | UNIVERSITY OF SASKATCHEWAN (CA) | 2024-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12151004-B2 | Methods and compositions for targeting disease related cell surface receptors using radiolabeled and/or cytotoxin labelled antibodies | CD47, HAVCR2, ASGR1 | SIGMAR1 288/4885CYP2C19 4626/4885SLC6A4 4110/4885 |
| US-20250127943-A1 | METHODS AND COMPOSITIONS FOR TARGETING DISEASE RELATED CELL SURFACE RECEPTORS USING RADIOLABELED AND/OR CYTOTOXIN LABELLED ANTIBODIES | CD47, HAVCR2, ASGR1 | SIGMAR1 288/4885CYP2C19 4626/4885SLC6A4 4110/4885 |
| US-20250339570-A1 | RADIOIMMUNOCONJUGATES AND THERAPEUTIC USES THEREOF | ITGA6, CD4, ITGB6 | SIGMAR1 1772/4885CYP2C19 4627/4885SLC6A4 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.