Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.63 |
| ▸ | F10 | P00742 | 12/20 | 0.55 |
| ▸ | FURIN | P09958 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31176875 | 1.00 | F2 (0.63) | F2F10FURINPRSS1PRSS2 | |
| SCHEMBL16741838 | 0.82 | AKR1C3 (0.59) | — | |
| SCHEMBL30967902 | 0.80 | NPC1 (0.47) | — | |
| SCHEMBL29237301 | 0.80 | NPC1 (0.47) | — | |
| SCHEMBL29336702 | 0.79 | F10 (0.64) | F2F10 | |
| SCHEMBL29336705 | 0.79 | F10 (0.55) | F2F10FURINPRSS1PRSS2 | |
| SCHEMBL563181 | 0.78 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL29336679 | 0.78 | KDR (0.54) | — | |
| SCHEMBL7974185 | 0.78 | F2 (0.75) | F2F10FURINPRSS1PRSS2 | |
| SCHEMBL443361 | 0.77 | NPC1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673137-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182736-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |