Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 3/20 | 0.50 |
| ▸ | PLAU | P00749 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28594480 | 0.90 | F2 (0.81) | F2CYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL31656329 | 0.85 | F2 (0.73) | F2PLGPLAUPRSS1KLKB1 | |
| SCHEMBL563033 | 0.85 | F2 (0.73) | F2PLGPLAUPRSS1KLKB1 | |
| Hydrochloric Acid SCHEMBL6786736 | 0.83 | F2 (0.71) | F2PLGPLAUPRSS1KLKB1 | |
| SCHEMBL27522161 | 0.81 | F2 (0.68) | F2CYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL29858415 | 0.81 | F2 (0.68) | F2CYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL170646 | 0.81 | F2 (0.68) | F2CYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL29540009 | 0.81 | F2 (0.68) | F2CYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL3708430 | 0.81 | F2 (0.68) | F2CYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL7340137 | 0.81 | F2 (0.65) | F2MAPTRAB9APLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086877-A1 | Small Molecule Inhibitors of Botulinum Neurotoxins | BAVARI SINA | 2011-04-14 | — | — | US | claimed |
| US-7825154-B2 | Small molecule inhibitors of botulinum neurotoxins | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2010-11-02 | — | — | US | claimed |
| EP-1945209-A2 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | United States Government As Represented By The Secretary of The United States Army And The U.S. Army Medical Research & Materiel Command (US) | 2008-07-23 | — | — | EP | claimed |
| WO-2008041966-A2 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U.S. ARMY MEDICAL RESEARCH & MATERIEL COMMAND (US) | 2008-04-10 | — | — | WO | claimed |
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2007-05-17 | — | — | US | claimed |
| US-20070112049-A1 | nonpeptidic inhibitors of Botulinum neurotoxin A metalloprotease activity, such as 2-[4-(4-carbamimidoylphenoxy)phenyl]-1H-indole-5-carboximidamide, used for treating, inhibiting or preventing intoxication caused by bacteria | ARMY, UNITED STATES | 2007-05-17 | — | — | US | claimed |
| EP-1140859-A2 | (HETERO)ARYL-BICYCLIC HETEROARYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035886-A2 | (HETERO)ARYL-BICYCLIC HETEROARYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-06-22 | — | — | WO | claimed |
| US-4397863-A | PROPHYLAXIS | RESEARCH TRIANGLE INSTITUTE (US) | 1983-08-09 | — | — | US | claimed |
| US-20250258182-A1 | ROCKY MOUNTAIN SPOTTED FEVER DETECTION AND TREATMENT | IDEXX LABORATORIES, INC. (US) | 2025-08-14 | — | — | US | disclosed |
| US-12228578-B2 | Rocky mountain spotted fever detection and treatment | IDEXX LABORATORIES, INC. (US) | 2025-02-18 | — | — | US | disclosed |
| CN-117715658-A | Method for inhibiting RAS | 锐新医药公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-4262860-A2 | ROCKY MOUNTAIN SPOTTED FEVER DETECTION AND TREATMENT | IDEXX Laboratories, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20220196672-A1 | Rocky Mountain Spotted Fever Detection and Treatment | IDEXX LABORATORIES, INC. (US) | 2022-06-23 | — | — | US | disclosed |
| US-4619942-A | Inhibition of Respiratory Syncytial virus-induced cell fusion by amidino compounds | UNIVERSITY OF NORTH CAROLINA (US) | 1986-10-28 | — | — | US | disclosed |
| US-4619942-A | Inhibition of Respiratory Syncytial virus-induced cell fusion by amidino compounds | UNIVERSITY OF NORTH CAROLINA (US) | 1986-10-28 | — | — | US | disclosed |
| US-4397863-A | PROPHYLAXIS | RESEARCH TRIANGLE INSTITUTE (US) | 1983-08-09 | — | — | US | disclosed |
| US-4397863-A | PROPHYLAXIS | RESEARCH TRIANGLE INSTITUTE (US) | 1983-08-09 | — | — | US | disclosed |
| US-4324794-A | PREVENTION OF EPIDEMICS BY PROPHYLACTIC ADMINISTRATION | RESEARCH TRIANGLE INSTITUTE (US) | 1982-04-13 | — | — | US | disclosed |
| US-4324794-A | PREVENTION OF EPIDEMICS BY PROPHYLACTIC ADMINISTRATION | RESEARCH TRIANGLE INSTITUTE (US) | 1982-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | MPO, CAT, LPO | F2 2171/4885CYP1A2 1275/4885CYP3A4 2834/4885 |
| US-20070112049-A1 | nonpeptidic inhibitors of Botulinum neurotoxin A metalloprotease activity, such as 2-[4-(4-carbamimidoylphenoxy)phenyl]-1H-indole-5-carboximidamide, used for treating, inhibiting or preventing intoxication caused by bacteria | ACHE, CTRL, MMP2 | F2 578/4885CYP1A2 1708/4885CYP3A4 2220/4885 |
| US-20110086877-A1 | Small Molecule Inhibitors of Botulinum Neurotoxins | ACHE, MMP2, TIMP3 | F2 521/4885CYP1A2 1858/4885CYP3A4 3573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.