Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25263628 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2CYP11B2HRH3 | |
| SCHEMBL25921437 | 0.88 | SMN1; SMN2 (0.34) | SMN1; SMN2CYP11B2HRH3 | |
| SCHEMBL26030296 | 0.87 | ALDH1A1 (0.38) | SMN1; SMN2 | |
| SCHEMBL30507222 | 0.82 | CYP11B2 (0.32) | SMN1; SMN2CYP11B2 | |
| SCHEMBL25316826 | 0.82 | CYP11B2 (0.32) | SMN1; SMN2CYP11B2 | |
| SCHEMBL30507184 | 0.82 | CYP11B2 (0.43) | SMN1; SMN2CYP11B2HRH3 | |
| SCHEMBL25314611 | 0.82 | CYP11B2 (0.43) | SMN1; SMN2CYP11B2HRH3 | |
| SCHEMBL25318355 | 0.79 | HDAC1 (0.36) | CYP11B2 | |
| SCHEMBL30507436 | 0.79 | HDAC1 (0.36) | CYP11B2 | |
| SCHEMBL25367161 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249254-A2 | METHODS OF USING APOL1 INHIBITORS | MAZE THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | WO | disclosed |