SCHEMBL31178428

SCHEMBL31178428

O=C1CC(c2ccncc2)=NO1

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.65
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
SORT1 Q99523 3/20 0.37
PDE3B Q13370 5/20 0.35
PDE3A Q14432 5/20 0.35
TP53 P04637 1/20 0.34
PKM P14618 1/20 0.34
CYP19A1 P11511 1/20 0.33
CDC7 O00311 2/20 0.32
KCNH2 Q12809 1/20 0.32
PTK2 Q05397 1/20 0.31
GAA P10253 1/20 0.31
MAPK14 Q16539 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181974 0.82 NOTUM (0.67) NOTUMLMNAMAPTSORT1GAA
SCHEMBL452337 0.78 NOTUM (0.68) NOTUMMAPTSORT1PDE3BPDE3A
SCHEMBL789358 0.78 NOTUM (0.68) NOTUMSORT1
SCHEMBL9782150 0.78 NOTUM (1.00) NOTUMLMNAMAPTSORT1PKM
SCHEMBL22925624 0.78 NOTUM (0.62) NOTUM
SCHEMBL11023401 0.74 NOTUM (0.62) NOTUMSORT1TP53
SCHEMBL20370831 0.74 NOTUM (0.67) NOTUMLMNAMAPTSORT1TP53
SCHEMBL14373829 0.74 NOTUM (0.62) NOTUMLMNAMAPTPKMGAA
SCHEMBL11717156 0.73 NOTUM (0.56) NOTUMSORT1TP53
SCHEMBL8597250 0.70 NOTUM (0.55) NOTUMLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049073-A1 SPECTACLE LENS COMPRISING AN ORGANIC DYE OAKLEY, INC. (US) 2026-02-19 US disclosed
WO-2024226717-A1 SPECTACLE LENS COMPRISING AN ORGANIC DYE OAKLEY, INC. (US) 2024-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049073-A1 SPECTACLE LENS COMPRISING AN ORGANIC DYE STRA6, TCOF1, CLIC1 NOTUM 3324/4885LMNA 1842/4885MAPT 2539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.