Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782441 | 1.00 | MEN1 (0.41) | MEN1KMT2APKMALDH1A1HPGD | |
| SCHEMBL17419138 | 0.93 | MEN1 (0.41) | MEN1KMT2APKMALDH1A1HPGD | |
| SCHEMBL24982338 | 0.81 | PKM (0.50) | MEN1KMT2APKMALDH1A1HPGD | |
| SCHEMBL30881275 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2APKMALDH1A1HPGD | |
| SCHEMBL16362387 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2APKMALDH1A1HPGD | |
| SCHEMBL19086642 | 0.80 | JAK2 (0.33) | MEN1KMT2APKMALDH1A1HPGD | |
| SCHEMBL29455589 | 0.79 | MEN1 (0.41) | MEN1KMT2APKMALDH1A1HPGD | |
| SCHEMBL748712 | 0.79 | PKM (0.41) | MEN1KMT2APKMALDH1A1HPGD | |
| SCHEMBL24981077 | 0.79 | MEN1 (0.41) | MEN1KMT2APKMALDH1A1HPGD | |
| SCHEMBL16362024 | 0.78 | MAPK1 (0.40) | MEN1KMT2APKMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222814-A1 | CYP11B2 INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 长春金赛药业有限责任公司 | 2024-10-31 | — | — | WO | disclosed |