Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4061563 | 0.89 | HTT (0.59) | HTTHPGDLMNAHSD17B10CASP1 | |
| SCHEMBL31181987 | 0.86 | HTT (0.97) | HTTHPGDLMNAHSD17B10CASP1 | |
| SCHEMBL16598992 | 0.83 | HTT (0.67) | HTTHPGDLMNAHSD17B10CASP1 | |
| SCHEMBL31182026 | 0.82 | HPGD (0.74) | HTTHPGDLMNAHSD17B10CASP1 | |
| SCHEMBL15963298 | 0.80 | HTT (0.70) | HTTHPGDLMNAHSD17B10CASP1 | |
| SCHEMBL31182007 | 0.78 | HTT (0.62) | HTTHPGDLMNAHSD17B10CASP1 | |
| SCHEMBL31182004 | 0.77 | HTT (0.65) | HTTHPGDLMNAHSD17B10CASP1 | |
| SCHEMBL7129676 | 0.77 | HPGD (0.79) | HPGDLMNAALDH1A1ALOX15MAOB | |
| SCHEMBL252026 | 0.77 | HPGD (0.79) | HPGDLMNAALDH1A1ALOX15MAOB | |
| SCHEMBL31181995 | 0.76 | WNT1 (0.49) | HTTHPGDLMNAHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878508-A | DC-Rhoin derivative, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-11-01 | — | — | CN | disclosed |