Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182004 | 0.85 | HTT (0.65) | HTTLMNAHPGDMAPTHSD17B10 | |
| SCHEMBL15963298 | 0.81 | HTT (0.70) | HTTLMNAHPGDMAPTHSD17B10 | |
| SCHEMBL31181994 | 0.79 | DYRK1A (0.48) | HTTLMNAHPGDMAPTSCD5 | |
| SCHEMBL31181987 | 0.79 | HTT (0.97) | HTTLMNAHPGDMAPTHSD17B10 | |
| SCHEMBL31181986 | 0.78 | HTT (0.74) | HTTLMNAHPGDMAPTHSD17B10 | |
| SCHEMBL8712806 | 0.77 | GFER (0.62) | HTTSCD5HRH1CCR3 | |
| SCHEMBL14597201 | 0.76 | ACHE (0.61) | HTTLMNAHPGDALDH1A1SCD5 | |
| SCHEMBL31182026 | 0.75 | HPGD (0.74) | HTTLMNAHPGDMAPTHSD17B10 | |
| SCHEMBL5271411 | 0.74 | EPHX2 (0.59) | SCD5EPHX2HRH1SRD5A1CYP2C9 | |
| SCHEMBL16598992 | 0.73 | HTT (0.67) | HTTLMNAHPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878508-A | DC-Rhoin derivative, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-11-01 | — | — | CN | disclosed |