Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.48 |
| ▸ | PIK3R2 | O00459 | 11/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.48 |
| ▸ | PIK3R5 | Q8WYR1 | 11/20 | 0.48 |
| ▸ | PIK3R3 | Q92569 | 11/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182011 | 0.87 | ALDH1A1 (0.53) | MEN1CYP1A2MAPTCYP2C9KMT2A | |
| SCHEMBL31182001 | 0.83 | HPGD (0.49) | TSHRHPGD | |
| SCHEMBL31182003 | 0.83 | HPGD (0.49) | TSHRHPGD | |
| SCHEMBL31181983 | 0.78 | HPGD (0.42) | MAPTKMT2APIK3CDPIK3R2PIK3CA | |
| SCHEMBL7121916 | 0.69 | SMN1; SMN2 (0.77) | MEN1KMT2ATSHRSMN1; SMN2HPGD | |
| SCHEMBL946143 | 0.68 | HPGD (0.86) | KMT2ATSHRSMN1; SMN2HPGDGAA | |
| SCHEMBL3996738 | 0.67 | TSHR (0.73) | MEN1CYP1A2CYP2C9KMT2ATSHR | |
| SCHEMBL9055138 | 0.67 | HPGD (0.44) | MEN1KMT2ATSHRSMN1; SMN2HPGD | |
| SCHEMBL30449295 | 0.66 | HPGD (0.83) | KMT2ATSHRSMN1; SMN2HPGDGAA | |
| Ammonia Solution, Strong SCHEMBL6028542 | 0.66 | HPGD (0.83) | KMT2ATSHRSMN1; SMN2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878508-A | DC-Rhoin derivative, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-11-01 | — | — | CN | disclosed |