Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182001 | 1.00 | HPGD (0.49) | HPGDALDH1A1USP2BLMSIGMAR1 | |
| SCHEMBL31182011 | 0.87 | ALDH1A1 (0.53) | HPGDALDH1A1USP2POLBTSHR | |
| SCHEMBL31182016 | 0.83 | MEN1 (0.57) | HPGDTSHR | |
| SCHEMBL31181983 | 0.78 | HPGD (0.42) | HPGDALDH1A1LMNAACHE | |
| SCHEMBL31182013 | 0.77 | WNT1 (0.51) | POLB | |
| SCHEMBL7129676 | 0.76 | HPGD (0.79) | HPGDALDH1A1USP2BLMSIGMAR1 | |
| SCHEMBL252026 | 0.76 | HPGD (0.79) | HPGDALDH1A1USP2BLMSIGMAR1 | |
| Hydrochloric Acid SCHEMBL1597472 | 0.74 | HPGD (0.76) | HPGDALDH1A1USP2BLMSIGMAR1 | |
| SCHEMBL4143496 | 0.71 | POLB (0.80) | HPGDALDH1A1USP2BLMSIGMAR1 | |
| SCHEMBL9410748 | 0.71 | HPGD (0.66) | HPGDALDH1A1USP2BLMSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878508-A | DC-Rhoin derivative, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-11-01 | — | — | CN | disclosed |