Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.62 |
| ▸ | HTR3A | P46098 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696607 | 0.90 | SLC6A2 (0.75) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL4407320 | 0.90 | SLC6A2 (0.75) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A | |
| SCHEMBL7062835 | 0.86 | DRD4 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2DRD4 | |
| SCHEMBL2244113 | 0.85 | SLC6A4 (0.59) | SLC6A2SLC6A4SLC6A3KCNH2DRD4 | |
| SCHEMBL8449011 | 0.85 | DRD4 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2DRD4 | |
| SCHEMBL507357 | 0.82 | DRD4 (0.48) | SLC6A2SLC6A4SLC6A3KCNH2DRD4 | |
| SCHEMBL3130245 | 0.82 | DRD4 (0.48) | SLC6A2SLC6A4SLC6A3KCNH2DRD4 | |
| SCHEMBL24493163 | 0.80 | HRH3 (0.61) | SLC6A2SLC6A4SLC6A3KCNH2DRD4 | |
| SCHEMBL29119715 | 0.80 | NAAA (0.59) | SLC6A2SLC6A4SLC6A3KCNH2DRD4 | |
| SCHEMBL18380998 | 0.79 | SLC6A4 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | SLC6A2 331/4885SLC6A4 438/4885SLC6A3 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.