Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.34 |
| ▸ | LIPE | Q05469 | 4/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17841555 | 1.00 | LPL (0.34) | LPLLIPGLIPECXCR2AAK1 | |
| SCHEMBL18865597 | 0.87 | LPL (0.36) | LPLLIPGLIPE | |
| SCHEMBL29691149 | 0.87 | LPL (0.36) | LPLLIPGLIPE | |
| SCHEMBL23295301 | 0.80 | LPL (0.32) | LPLLIPGLIPE | |
| SCHEMBL29412362 | 0.80 | LPL (0.32) | LPLLIPGLIPE | |
| SCHEMBL23295300 | 0.80 | LPL (0.32) | LPLLIPGLIPE | |
| SCHEMBL31467992 | 0.80 | LPL (0.32) | LPLLIPGLIPE | |
| SCHEMBL31046590 | 0.78 | LPL (0.40) | LPLLIPGLIPECXCR2JAK2 | |
| SCHEMBL2813914 | 0.78 | LPL (0.40) | LPLLIPGLIPECXCR2JAK2 | |
| SCHEMBL18059686 | 0.77 | TRPV4 (0.46) | LPLLIPGLIPEAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220641-A1 | 1,6-NAPHTHYRIDINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 USEFUL FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | VANDERBILT UNIVERSITY (US) | 2024-10-24 | — | — | WO | disclosed |