Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18328487 | 0.98 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL28456562 | 0.96 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL29041433 | 0.78 | OPRL1 (0.34) | OPRL1 | |
| SCHEMBL24983176 | 0.74 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL21287272 | 0.74 | KDM4E (0.38) | OPRL1 | |
| SCHEMBL28907374 | 0.74 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL18319815 | 0.73 | OPRL1 (0.32) | OPRL1 | |
| Potassium Ion SCHEMBL29187779 | 0.73 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL28645007 | 0.70 | KDM5A (0.35) | OPRL1 | |
| SCHEMBL23022442 | 0.70 | P2RX7 (0.35) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112625028-B | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2024-10-29 | — | — | CN | disclosed |