Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184914 | 0.85 | TYK2 (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTTYK2 | |
| SCHEMBL31184856 | 0.84 | TYK2 (0.47) | RAB9AKMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL31184518 | 0.83 | TP53 (0.49) | RAB9AKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31184817 | 0.79 | MAPT (0.43) | RAB9AKMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL31184972 | 0.78 | POLB (0.44) | RAB9AKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31184973 | 0.78 | POLB (0.44) | RAB9AKMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31184906 | 0.78 | ACHE (0.43) | KMT2AALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL31184788 | 0.77 | POLB (0.44) | KMT2AALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL31184581 | 0.77 | POLB (0.42) | RAB9AALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL31184585 | 0.77 | CHKA (0.44) | KMT2AALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |