SCHEMBL31184429

SCHEMBL31184429

CC(C)(N)C(=O)N[C@@H](CCCNC(N)=O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ C3AR1 Q16581 1/20 0.47
▸ SHMT1 P34896 1/20 0.44
▸ CTDSP1 Q9GZU7 1/20 0.43
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ KLK7 P49862 1/20 0.41
▸ FOLH1 Q04609 7/20 0.40
▸ GAA P10253 1/20 0.39
▸ NOD1 Q9Y239 3/20 0.38
▸ POLB P06746 1/20 0.38
▸ GNPAT O15228 2/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24805405 0.89 C3AR1 (0.48) C3AR1SHMT1CTDSP1MEN1KMT2A
SCHEMBL31184339 0.88 FOLH1 (0.39) C3AR1SHMT1CTDSP1MEN1KMT2A
SCHEMBL5497855 0.82 C3AR1 (0.55) C3AR1SHMT1CTDSP1MEN1KMT2A
SCHEMBL5497852 0.82 C3AR1 (0.55) C3AR1SHMT1CTDSP1MEN1KMT2A
SCHEMBL29982298 0.81 FOLH1 (0.49) FOLH1NOD1GNPAT
SCHEMBL468877 0.81 FOLH1 (0.51) C3AR1SHMT1CTDSP1MEN1KMT2A
SCHEMBL468875 0.81 FOLH1 (0.51) C3AR1SHMT1CTDSP1MEN1KMT2A
SCHEMBL29476375 0.81 NOD1 (0.47) FOLH1NOD1
SCHEMBL28919107 0.81 MEN1 (0.43) C3AR1SHMT1CTDSP1MEN1KMT2A
SCHEMBL31184484 0.80 NPY4R (0.49) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025042770-A1 ANOREXIA-SENSITIZING AGENTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-02-27 — — WO disclosed
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R C3AR1 2341/4885SHMT1 3594/4885CTDSP1 4311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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