Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184345 | 0.87 | POLB (0.42) | GRM1MAPTMALT1KMT2ACYP3A4 | |
| SCHEMBL31184905 | 0.87 | GRM1 (0.40) | GRM1GAAATMGRM4MALT1 | |
| SCHEMBL31184599 | 0.85 | MEN1 (0.40) | GRM1MAPTGAAATMGRM4 | |
| SCHEMBL31184754 | 0.82 | MAPT (0.47) | GRM1MAPTKMT2A | |
| SCHEMBL31184873 | 0.81 | GAA (0.41) | GRM1MAPTGAAATM | |
| SCHEMBL31184973 | 0.78 | POLB (0.44) | MAPTMALT1KMT2ACYP3A4 | |
| SCHEMBL31184972 | 0.78 | POLB (0.44) | MAPTMALT1KMT2ACYP3A4 | |
| SCHEMBL31184761 | 0.77 | MAPT (0.43) | MAPTMALT1KMT2AMEN1CYP3A4 | |
| SCHEMBL31184861 | 0.77 | POLB (0.43) | MAPTMALT1KMT2ACYP3A4 | |
| SCHEMBL31184573 | 0.77 | MALT1 (0.46) | GRM1GRM4MALT1KMT2AGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |