Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184564 | 0.90 | CACNA1H (0.35) | MEN1KMT2ARAB9AGRM1ALDH1A1 | |
| SCHEMBL31184453 | 0.85 | GRM1 (0.40) | MEN1KMT2AGRM1MAPTGAA | |
| SCHEMBL31184345 | 0.82 | POLB (0.42) | KMT2ARAB9AGRM1ALDH1A1HPGD | |
| SCHEMBL31184754 | 0.82 | MAPT (0.47) | KMT2ARAB9AGRM1LMNAMAPT | |
| SCHEMBL31184905 | 0.81 | GRM1 (0.40) | GRM1ALDH1A1GAAATMSMN1; SMN2 | |
| SCHEMBL31184873 | 0.80 | GAA (0.41) | GRM1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL31184972 | 0.74 | POLB (0.44) | KMT2ARAB9AALDH1A1HPGDLMNA | |
| SCHEMBL31184973 | 0.74 | POLB (0.44) | KMT2ARAB9AALDH1A1HPGDMAPT | |
| SCHEMBL31184716 | 0.73 | NPSR1 (0.47) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL31184861 | 0.73 | POLB (0.43) | KMT2ARAB9AALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |