Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185096 | 0.92 | FPR2 (0.38) | GAAATMGRM1L3MBTL1THRB | |
| SCHEMBL31184345 | 0.82 | POLB (0.42) | GRM1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31184453 | 0.81 | GRM1 (0.40) | GAAATMGRM1MAPT | |
| SCHEMBL31184754 | 0.81 | MAPT (0.47) | GRM1L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL31184599 | 0.80 | MEN1 (0.40) | GAAATMGRM1THRBMAPT | |
| SCHEMBL31184905 | 0.78 | GRM1 (0.40) | GAAATMGRM1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31184839 | 0.76 | IDH1 (0.39) | GAAGRM1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL31184843 | 0.73 | POLB (0.41) | MAPTALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL31184973 | 0.73 | POLB (0.44) | MAPTALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL31184972 | 0.73 | POLB (0.44) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |