Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31184864 | 0.82 | HTR2B (0.48) | MAPK1PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL31185072 | 0.81 | MAPK1 (0.49) | MAPK1PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL31184760 | 0.76 | MAPK1 (0.40) | MAPK1PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL30659847 | 0.76 | PARP1 (0.49) | MAPK1HTR2CHTR2BHTR2ACDK4 | |
| SCHEMBL31184759 | 0.76 | MAPK1 (0.40) | MAPK1PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL22733298 | 0.76 | CRBN (0.49) | MAPK1PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL5501922 | 0.75 | CRBN (0.38) | MAPK1PIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL31184880 | 0.74 | MAPK1 (0.45) | MAPK1LRRK2HTR2CHTR2BHTR2A | |
| SCHEMBL31184839 | 0.74 | IDH1 (0.39) | MAPK1HTR2CHTR2BHTR2ACDK4 | |
| SCHEMBL1333882 | 0.73 | PIM1 (0.46) | PIM1CSNK1A1CDK5ROCK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |