Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184632 | 0.87 | MAPK1 (0.46) | MAPK1IDH1RAB9AALDH1A1CDK4 | |
| SCHEMBL31184574 | 0.81 | ACE (0.37) | ALDH1A1HTTSMN1; SMN2BTKSLC6A4 | |
| SCHEMBL31184345 | 0.78 | POLB (0.42) | MAPK1RAB9AALDH1A1SMN1; SMN2GRM1 | |
| SCHEMBL31184821 | 0.78 | MAPT (0.42) | ALDH1A1HTT | |
| SCHEMBL31185072 | 0.76 | MAPK1 (0.49) | MAPK1IDH1CDK4LRRK2CRBN | |
| SCHEMBL31184482 | 0.75 | TP53 (0.48) | — | |
| SCHEMBL31184760 | 0.74 | MAPK1 (0.40) | MAPK1IDH1CDK4LRRK2CRBN | |
| SCHEMBL31184759 | 0.74 | MAPK1 (0.40) | MAPK1IDH1CDK4LRRK2CRBN | |
| SCHEMBL31184577 | 0.74 | MAPK1 (0.46) | MAPK1IDH1CDK4LRRK2CRBN | |
| SCHEMBL31184529 | 0.73 | MAPK1 (0.49) | MAPK1IDH1CDK4CRBNHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |