Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184643 | 0.87 | PARP1 (0.37) | MAPTPOLBGRM4PARP1CNR1 | |
| SCHEMBL31184638 | 0.87 | PARP1 (0.37) | MAPTPOLBGRM4PARP1CNR1 | |
| SCHEMBL31184972 | 0.84 | POLB (0.44) | MAPTPOLBLMNA | |
| SCHEMBL31184672 | 0.83 | MAPT (0.36) | MAPTGRM4PARP1CNR1CNR2 | |
| SCHEMBL31185021 | 0.80 | MAPT (0.36) | MAPTPOLBPARP1CNR1CNR2 | |
| SCHEMBL31184475 | 0.79 | POLB (0.49) | MAPTPOLBLMNA | |
| SCHEMBL31184973 | 0.79 | POLB (0.44) | MAPTPOLBHTR2C | |
| SCHEMBL31184761 | 0.78 | MAPT (0.43) | MAPTPOLBLMNA | |
| SCHEMBL31184451 | 0.77 | GRM4 (0.44) | MAPTPOLBGRM4CNR1CNR2 | |
| SCHEMBL31184640 | 0.77 | POLB (0.45) | MAPTPOLBHTR2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |