Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184478 | 0.94 | MAPT (0.38) | MAPTCRHBPCRHR2CNR1CNR2 | |
| SCHEMBL31184793 | 0.92 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL31184867 | 0.91 | ALDH1A1 (0.44) | MAPTCRHBPCRHR2CNR1CNR2 | |
| SCHEMBL31184643 | 0.88 | PARP1 (0.37) | MAPTCRHBPCRHR2CNR1CNR2 | |
| SCHEMBL31184638 | 0.88 | PARP1 (0.37) | MAPTCRHBPCRHR2CNR1CNR2 | |
| SCHEMBL31184987 | 0.85 | HTR2B (0.36) | MAPTCRHBPCRHR2 | |
| SCHEMBL31184359 | 0.85 | POLB (0.47) | MAPTALDH1A1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL31184778 | 0.83 | MAPT (0.40) | MAPTCNR1CNR2GRM4PARP1 | |
| SCHEMBL31184984 | 0.83 | HTR2A (0.38) | MAPTCRHBPCRHR2PARP1MEN1 | |
| SCHEMBL31185021 | 0.82 | MAPT (0.36) | MAPTCRHBPCRHR2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |