Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27610033 | 0.84 | ALDH1A1 (0.46) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL8325905 | 0.82 | L3MBTL1 (0.46) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL31368236 | 0.81 | CA12 (0.44) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL16726632 | 0.81 | CA12 (0.44) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL31145860 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL29274165 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL1178762 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL16649076 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL17948707 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL31720064 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1GAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |