Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184693 | 0.87 | MALT1 (0.45) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184586 | 0.86 | POLB (0.41) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL31184740 | 0.84 | IMPDH2 (0.47) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL31184818 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL31184656 | 0.83 | POLB (0.40) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL31184972 | 0.83 | POLB (0.44) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL31184508 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL31184841 | 0.81 | POLB (0.45) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL31184973 | 0.81 | POLB (0.44) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL31184510 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |