Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184724 | 0.88 | TP53 (0.43) | MALT1KMT2ALMNAHPGDHTT | |
| SCHEMBL31185080 | 0.86 | MALT1 (0.53) | MALT1HPGDSMN1; SMN2 | |
| SCHEMBL31184812 | 0.85 | MGLL (0.48) | MGLLMALT1EPHX2MEN1KMT2A | |
| SCHEMBL31184910 | 0.84 | TRPV1 (0.40) | TRPV1MEN1KMT2AMAPTLMNA | |
| SCHEMBL31184406 | 0.83 | POLB (0.43) | MALT1TRPV1MAPTLMNAHPGD | |
| SCHEMBL31185102 | 0.83 | POLB (0.44) | MALT1TRPV1MAPTLMNAHPGD | |
| SCHEMBL31184771 | 0.82 | RXFP2 (0.44) | TRPV1EPHX2MEN1KMT2A | |
| SCHEMBL31184899 | 0.82 | MALT1 (0.45) | MALT1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL31184551 | 0.81 | TP53 (0.41) | MALT1TRPV1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL31185043 | 0.80 | POLB (0.41) | MALT1TRPV1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |