Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185043 | 0.92 | POLB (0.41) | TRPV1SMN1; SMN2POLBKMT2ANPSR1 | |
| SCHEMBL31184830 | 0.90 | SMN1; SMN2 (0.41) | TRPV1SMN1; SMN2UBE2MDCUN1D1KDM4E | |
| SCHEMBL31185102 | 0.86 | POLB (0.44) | TRPV1SMN1; SMN2POLBLMNAALDH1A1 | |
| SCHEMBL31184660 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2UBE2MDCUN1D1KDM4EMEN1 | |
| SCHEMBL31184406 | 0.84 | POLB (0.43) | TRPV1SMN1; SMN2POLBNPSR1LMNA | |
| SCHEMBL31184771 | 0.84 | RXFP2 (0.44) | TRPV1KDM4EMEN1POLBKMT2A | |
| SCHEMBL31184895 | 0.84 | MGLL (0.47) | TRPV1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL31184995 | 0.83 | MALT1 (0.41) | TRPV1SMN1; SMN2POLBKMT2AALDH1A1 | |
| SCHEMBL31185080 | 0.82 | MALT1 (0.53) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL31184724 | 0.82 | TP53 (0.43) | SMN1; SMN2POLBKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |