Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185049 | 0.92 | ALDH1A1 (0.44) | ALDH1A1GAAKMT2ANPC1RAB9A | |
| SCHEMBL31184657 | 0.92 | ALDH1A1 (0.44) | ALDH1A1GAAKMT2ANPC1RAB9A | |
| SCHEMBL31184994 | 0.91 | GRM1 (0.44) | ALDH1A1GAAKMT2AMEN1NPC1 | |
| SCHEMBL31184399 | 0.91 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL31184655 | 0.90 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL31184660 | 0.90 | SMN1; SMN2 (0.42) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL31184972 | 0.89 | POLB (0.44) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31184640 | 0.89 | POLB (0.45) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31184350 | 0.89 | MAPK14 (0.42) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31184763 | 0.89 | EPHX2 (0.49) | ALDH1A1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |