Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184763 | 0.94 | EPHX2 (0.49) | GRM1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL31184812 | 0.92 | MGLL (0.48) | GRM1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL31184979 | 0.91 | ALDH1A1 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL31184745 | 0.91 | GRM1 (0.44) | GRM1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL31184499 | 0.90 | MALT1 (0.46) | GRM1SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL31184657 | 0.89 | ALDH1A1 (0.44) | GRM1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL31184902 | 0.88 | MALT1 (0.54) | SMN1; SMN2ALDH1A1TSHRHPGDMALT1 | |
| SCHEMBL31184660 | 0.87 | SMN1; SMN2 (0.42) | GRM1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL31185049 | 0.87 | ALDH1A1 (0.44) | GRM1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL31185026 | 0.86 | KMT2A (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |