Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936332 | 0.85 | TSHR (0.40) | ALDH1A1TSHRTHRB | |
| SCHEMBL9137953 | 0.81 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL10602322 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL10874823 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRTHRB | |
| SCHEMBL2407881 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL7794932 | 0.74 | HCAR2 (0.40) | — | |
| SCHEMBL3622864 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9714998 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL10769972 | 0.73 | TSHR (0.37) | ALDH1A1TSHRTHRB | |
| SCHEMBL10595376 | 0.72 | THRB (0.31) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640221-B1 | SURFACE WETTABLE SILICONE HYDROGELS | BAUSCH & LOMB (US) | 1997-07-16 | — | — | EP | claimed |
| EP-0640221-A1 | SURFACE WETTABLE SILICONE HYDROGELS. | BAUSCH & LOMB (US) | 1995-03-01 | — | — | EP | claimed |
| US-5387632-A | A contact lens is made of a hydrolyzed addition-condensation copolymers consisting the precuser of an acrylic-capped polysiloxanes, a bulky polysiloxanylalkyl (meth)acrylate and hydrophilic monomers; oxygen permeability; medical devices | BAUSCH & LOMB INCORPORATED (US) | 1995-02-07 | — | — | US | claimed |
| US-5358995-A | Containing acrylic endcapped polysiloxane and a polysiloxanylalkyl (meth)acrylate | BAUSCH & LOMB INCORPORATED (US) | 1994-10-25 | — | — | US | claimed |
| US-5334681-A | High oxygen permeability; resiliency, flexibility; wettability; biocompatibility | CIBA-GEIGY CORPORATION (US) | 1994-08-02 | — | — | US | claimed |
| WO-1993023774-A1 | SURFACE WETTABLE SILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 1993-11-25 | — | — | WO | claimed |
| US-5115056-A | FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | claimed |
| JP-4175316-A | — | — | None | — | — | JP | disclosed |
| JP-4168116-A | — | — | None | — | — | JP | disclosed |
| JP-4023819-A | — | — | None | — | — | JP | disclosed |
| JP-59166547-A | — | — | None | — | — | JP | disclosed |
| US-11866531-B2 | Oil-resistant lens material and ophthalmic devices | Twenty Twenty Therapeutrics LLC (US) | 2024-01-09 | — | — | US | disclosed |
| US-20210317297-A1 | METHODS AND COMPOSITION OF A DENTAL MODEL FOR THE MANUFACTURE OF ORTHODONTIC APPLIANCES WITHOUT THE USE OF SEPARATOR | STRUCTO PTE LTD (SG) | 2021-10-14 | — | — | US | disclosed |
| US-4594401-A | Oxygen permeable hard contact lens formed from styrene monomer containing a silyl or siloxane group | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| US-4540761-A | FLUOROALKYL ACRYLATE, SILOXANE METHACRYLATE | HOYA LENS CORPORATION (JP) | 1985-09-10 | — | — | US | disclosed |
| JP-S59166547-A | VINYL CHLORIDE RESIN COMPOSITION | SHIN ETSU CHEM CO LTD | 1984-09-19 | — | — | JP | disclosed |
| US-4433125-A | COPOLYMER OF SILICON CONTAINING ACRYLATE OR METHACRYLATE, AND FLUOROALKYL ACRYLATE OR METHACRYLATE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1984-02-21 | — | — | US | disclosed |
| US-RE31406-E | POLYSILOXANYLALKYL ACRYLATE AND ALKYL ACRYLATE COPOLYMER | SYNTEX (U.S.A.) INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4182822-A | VINYL AMIDES, ESTERS OF SILANE COMPOUNDS, CONTACT LENSES | CHANG SING HSIUNG | 1980-01-08 | — | — | US | disclosed |
| US-4120570-A | POLYSILOXANYLALKYL ACRYLATE OR METHACRYLATE AND AN ALKYL ACRYLATE OR METHACRYLATE | SYNTEX (U.S.A.) INC. (US) | 1978-10-17 | — | — | US | disclosed |