Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18512319 | 0.84 | HSD17B10 (0.49) | HSD17B10NOTUMKDM4EPKMTUBB1 | |
| SCHEMBL31500456 | 0.84 | HSD17B10 (0.49) | HSD17B10NOTUMKDM4EPKMTUBB1 | |
| SCHEMBL643173 | 0.77 | AAK1 (0.39) | USP30MTNR1AMTNR1BMAPTNOTUM | |
| SCHEMBL643318 | 0.76 | DGAT1 (0.54) | USP30MAPTAAK1DGAT1 | |
| SCHEMBL30362190 | 0.76 | USP30 (0.43) | USP30MAPTKDM4EAAK1DGAT1 | |
| SCHEMBL1185728 | 0.76 | USP30 (0.43) | USP30MAPTKDM4EAAK1DGAT1 | |
| SCHEMBL34472958 | 0.76 | TPMT (0.43) | HSD17B10MTNR1AMTNR1BMAPTNOTUM | |
| SCHEMBL21591073 | 0.76 | MTNR1A (0.41) | HSD17B10USP30MTNR1AMTNR1BMAPT | |
| SCHEMBL10228045 | 0.76 | TUBB1 (0.41) | HSD17B10MTNR1AMTNR1BKDM4ETUBB1 | |
| SCHEMBL20570499 | 0.75 | HSD17B10 (0.46) | HSD17B10MTNR1AMTNR1BMAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024254534-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | INTERLINE THERAPEUTICS, INC. (US) | 2024-12-12 | — | — | WO | disclosed |