Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 6/20 | 0.53 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30403358 | 0.79 | METAP2 (0.56) | METAP2METIDO1TDO2CYP1A2 | |
| SCHEMBL3538351 | 0.79 | METAP2 (0.56) | METAP2METIDO1TDO2CYP1A2 | |
| SCHEMBL14487466 | 0.79 | METAP2 (0.56) | METAP2NOS1IDO1TDO2DYRK1A | |
| SCHEMBL7909516 | 0.76 | METAP2 (0.53) | METAP2NOS1METIDO1TDO2 | |
| SCHEMBL3513796 | 0.76 | METAP2 (0.53) | METAP2METIDO1TDO2 | |
| SCHEMBL29793852 | 0.76 | METAP2 (0.53) | METAP2NOS1METIDO1TDO2 | |
| SCHEMBL16618130 | 0.76 | IDO1 (0.61) | METAP2NOS1IDO1TDO2DYRK1A | |
| SCHEMBL30860872 | 0.76 | IDO1 (0.61) | METAP2METIDO1TDO2CYP1A2 | |
| SCHEMBL7572191 | 0.76 | NOS1 (0.50) | METAP2NOS1IDO1TDO2DYRK1A | |
| SCHEMBL29410369 | 0.76 | IDO1 (0.61) | METAP2NOS1IDO1TDO2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220747-A2 | FLUORINATED CYCLIC DERIVATIVES OF SULFONAMIDES AND SULFONES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2024-10-24 | — | — | WO | disclosed |