Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.39 |
| ▸ | IL1B | P01584 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31190796 | 0.85 | P2RX7 (0.38) | DGAT2P2RX7IL1BHPGDALDH1A1 | |
| SCHEMBL31190648 | 0.81 | CYP4F2 (0.35) | DGAT2RETMAP3K5PDE10ARXRA | |
| SCHEMBL31190737 | 0.81 | DGAT2 (0.36) | DGAT2P2RX7IL1BHPGDALDH1A1 | |
| SCHEMBL31586782 | 0.81 | RET (0.40) | DGAT2RETPDE10ARXRARXRB | |
| SCHEMBL29005562 | 0.80 | ESR1 (0.42) | DGAT2HPGDALDH1A1RETMAP3K5 | |
| SCHEMBL29363550 | 0.79 | MAP3K5 (0.37) | DGAT2ALDH1A1RETMAP3K5KDM4E | |
| SCHEMBL1513052 | 0.79 | MAP3K5 (0.37) | DGAT2ALDH1A1RETMAP3K5KDM4E | |
| SCHEMBL31190685 | 0.77 | DGAT2 (0.36) | DGAT2P2RX7IL1BHPGDALDH1A1 | |
| SCHEMBL26404836 | 0.77 | DGAT2 (0.39) | DGAT2P2RX7IL1BHPGDALDH1A1 | |
| SCHEMBL16634070 | 0.77 | CYP4F2 (0.37) | DGAT2HPGDALDH1A1RETMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220747-A2 | FLUORINATED CYCLIC DERIVATIVES OF SULFONAMIDES AND SULFONES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2024-10-24 | — | — | WO | disclosed |