Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.52 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.52 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.51 |
| ▸ | CALCR | P30988 | 1/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.50 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | GLP1R | P43220 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | GIPR | P48546 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31191392 | 0.96 | OPRD1 (0.52) | MAPK8MAPK9MAPK10KEAP1OPRD1 | |
| SCHEMBL31191418 | 0.96 | NMUR2 (0.56) | MAPK8MAPK9MAPK10KEAP1OPRD1 | |
| SCHEMBL29679870 | 0.89 | MAPK8 (0.54) | MAPK8MAPK9MAPK10KEAP1NMUR2 | |
| SCHEMBL31191279 | 0.88 | MAPK8 (0.58) | MAPK8MAPK9MAPK10KEAP1OPRD1 | |
| SCHEMBL30429026 | 0.86 | RAMP3 (0.58) | MAPK8MAPK9MAPK10KEAP1NMUR2 | |
| SCHEMBL31419694 | 0.85 | OPRD1 (0.56) | MAPK8MAPK9MAPK10KEAP1OPRD1 | |
| SCHEMBL29730643 | 0.85 | KEAP1 (0.56) | KEAP1OPRD1NMUR2NMUR1RAMP3 | |
| SCHEMBL30429680 | 0.85 | EP300 (0.61) | MAPK8MAPK9MAPK10KEAP1CALCR | |
| SCHEMBL31119607 | 0.85 | IL23R (0.54) | MAPK8MAPK9MAPK10KEAP1NMUR2 | |
| SCHEMBL30176479 | 0.84 | MAPK8 (0.57) | MAPK8MAPK9MAPK10KEAP1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166266-B | Anti-mesothelin constructs and uses thereof | 上海偌妥生物科技有限公司 | 2025-06-24 | — | — | CN | disclosed |
| US-12215130-B2 | Cytokine-albumin binding moiety fusion proteins and uses thereof | ANWITA BIOSCIENCES, INC. (US) | 2025-02-04 | — | — | US | disclosed |
| US-12091438-B2 | Anti-mesothelin constructs and uses thereof | ANWITA BIOSCIENCES, INC. (US) | 2024-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12091438-B2 | Anti-mesothelin constructs and uses thereof | IL15, IL15RA, EPS15 | MAPK8 2972/4885MAPK9 2847/4885MAPK10 1764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.