Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981356 | 1.00 | CA12 (0.49) | CA12CA1CA9CYP17A1ACHE | |
| SCHEMBL5891978 | 0.88 | CA12 (0.49) | CA12CA1CA9CYP17A1ACHE | |
| SCHEMBL17903073 | 0.87 | CA12 (0.45) | CA12CA1CA9CYP17A1ACHE | |
| SCHEMBL17903007 | 0.85 | CA12 (0.55) | CA12CA1CA9CYP17A1MEN1 | |
| SCHEMBL5425869 | 0.85 | CA12 (0.49) | CA12CA1CA9CYP17A1ACHE | |
| SCHEMBL10013751 | 0.84 | CA12 (0.48) | CA12CA1CA9CYP17A1MEN1 | |
| SCHEMBL29953842 | 0.84 | CA12 (0.48) | CA12CA1CA9CYP17A1MAP4K4 | |
| SCHEMBL17790710 | 0.84 | CA12 (0.48) | CA12CA1CA9CYP17A1MAP4K4 | |
| SCHEMBL29956706 | 0.84 | CA12 (0.48) | CA12CA1CA9CYP17A1MAP4K4 | |
| SCHEMBL28423282 | 0.83 | CA12 (0.51) | CA12CA1CA9CYP17A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222918-A1 | BENZO SIX-MEMBERED HETEROCYCLIC GSPT1 PROTEIN DEGRADATION AGENT AND USE THEREOF | 中国药科大学 | 2024-10-31 | — | — | WO | disclosed |