Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746176 | 0.93 | CA12 (0.49) | CA12CA1CA9CYP17A1RXFP1 | |
| SCHEMBL24690021 | 0.88 | CA12 (0.46) | CA12CA1CA9CYP17A1RXFP1 | |
| SCHEMBL29956441 | 0.87 | HPGD (0.46) | CA12CA1CA9CYP17A1RXFP1 | |
| SCHEMBL3292146 | 0.87 | HPGD (0.46) | CA12CA1CA9CYP17A1RXFP1 | |
| SCHEMBL5419583 | 0.86 | CA12 (0.43) | CA12CA1CA9CYP17A1RXFP1 | |
| SCHEMBL5419579 | 0.86 | CA12 (0.43) | CA12CA1CA9CYP17A1RXFP1 | |
| SCHEMBL17903007 | 0.85 | CA12 (0.55) | CA12CA1CA9CYP17A1MAP4K4 | |
| SCHEMBL31192035 | 0.85 | CA12 (0.49) | CA12CA1CA9CYP17A1MAP4K4 | |
| SCHEMBL2981356 | 0.85 | CA12 (0.49) | CA12CA1CA9CYP17A1MAP4K4 | |
| SCHEMBL29954656 | 0.85 | KCNQ4 (0.46) | CA12CA1CA9CYP17A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101090882-A | P-diaminobenzene derivatives and dyes containing these compounds | PROCTER & GAMBLE (US) | 2007-12-19 | — | — | CN | disclosed |
| US-20070169287-A1 | P-diaminobenzene derivatives and dyes containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-07-26 | — | — | US | disclosed |
| US-6800097-B2 | FOR DYEING KERATIN FIBERS; HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-10-05 | — | — | US | disclosed |
| US-6780998-B2 | DEVELOPER-COUPLER SUBSTANCE COMBINATION HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-24 | — | — | US | disclosed |
| US-6699990-B2 | COLORFASTNESS; WATERPROOFING; OXIDATIVE COLOR HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-6685751-B2 | SUCH AS 2-((2-AMINO-PHENYLAMINO)-METHYL)-1,4-DIAMINOBENZENE; HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-6602302-B1 | Mixtures of carbocyclic amines such as 2-((2-aminophenylamino) -methyl)-1,4-diaminobenzene, couplers and developers, having photostability, wash and colorfastness, used for dyeing human hair | WELLA AG (DE) | 2003-08-05 | — | — | US | disclosed |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-31 | — | — | US | disclosed |
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | disclosed |
| US-20030070241-A1 | Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-04-17 | — | — | US | disclosed |
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-12-19 | — | — | US | disclosed |
| US-6436152-B1 | Substituted 2-aminoalky-1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020189033-A1 | Substituted 2-aminoalkyl-1,4diaminobenzene compounds and oxidation dye precursor compositions containing same | DDT, CYP1B1, ALDH7A1 | CA12 1530/4885CA1 1545/4885CA9 1583/4885 |
| US-20070169287-A1 | P-diaminobenzene derivatives and dyes containing these compounds | KRT18, DSP, DSG1 | CA12 1005/4885CA1 1885/4885CA9 1848/4885 |
| US-20030070241-A1 | Substituted 2-aminoalkyl-1,4-Diaminobenzene compounds and oxidation dye precursor compositions containing same | DDT, ALDH7A1, DDC | CA12 1314/4885CA1 1357/4885CA9 1442/4885 |
| US-20030140431-A1 | 3-(2,5-Diaminophenyl)-acrylamide derivatives and colouring agents containing said compounds | DPYD, AOC1, GPX4 | CA12 3368/4885CA1 2853/4885CA9 2883/4885 |
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | KRT18, AOC1, DAO | CA12 855/4885CA1 627/4885CA9 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.