Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31192035 | 0.88 | CA12 (0.49) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL2981356 | 0.88 | CA12 (0.49) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL20157610 | 0.84 | CA12 (0.48) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL29955042 | 0.84 | CA12 (0.48) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL31662881 | 0.84 | CA12 (0.48) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL29956706 | 0.84 | CA12 (0.48) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL28423282 | 0.83 | CA12 (0.51) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL5425869 | 0.82 | CA12 (0.49) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL17903007 | 0.82 | CA12 (0.55) | CA12CA1CA9MAP4K4CYP17A1 | |
| SCHEMBL27289068 | 0.82 | CA12 (0.46) | CA12CA1CA9MAP4K4CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079357-A1 | TNIK MODULATORS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2019-04-25 | — | — | WO | disclosed |
| US-7109043-B2 | Fluorescent probe for magnesium ion determination | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20040044228-A1 | Fluorescent probe for magnesium ion determination | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044228-A1 | Fluorescent probe for magnesium ion determination | MGST1, CA2, MRM1 | CA12 314/4885CA1 20/4885CA9 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.