Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 10/20 | 0.44 |
| ▸ | UBE2M | P61081 | 9/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116461 | 0.89 | ROCK2 (0.47) | ROCK2NTRK1DCUN1D1UBE2M | |
| SCHEMBL3249296 | 0.79 | ROCK2 (0.77) | ROCK2NTRK1ROCK1 | |
| SCHEMBL3116464 | 0.78 | HSP90AA1 (0.42) | ROCK2NTRK1 | |
| SCHEMBL4525156 | 0.76 | ROCK2 (0.63) | ROCK2ROCK1MEN1KMT2A | |
| SCHEMBL24174774 | 0.74 | ROCK2 (0.61) | ROCK2ROCK1MEN1KMT2A | |
| SCHEMBL31396420 | 0.74 | ROCK2 (0.61) | ROCK2ROCK1MEN1KMT2A | |
| SCHEMBL27744384 | 0.72 | ROCK2 (0.48) | ROCK2ROCK1 | |
| SCHEMBL4525158 | 0.72 | ROCK2 (0.48) | ROCK2ROCK1 | |
| SCHEMBL9265728 | 0.72 | AGER (0.56) | ROCK2NTRK1DCUN1D1UBE2M | |
| SCHEMBL3816834 | 0.72 | ROCK1 (0.56) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |