Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 8/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | IL1RN | P18510 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21225183 | 1.00 | AKR1C3 (0.71) | AKR1C3MAPTIL1RNF2PRSS1 | |
| SCHEMBL30921570 | 0.93 | AKR1C3 (0.68) | AKR1C3MAPTIL1RNF2PRSS1 | |
| SCHEMBL2566255 | 0.93 | AKR1C3 (0.68) | AKR1C3MAPTIL1RNF2PRSS1 | |
| SCHEMBL1000570 | 0.92 | AKR1C3 (0.66) | AKR1C3MAPTIL1RNF2PRSS1 | |
| SCHEMBL16408484 | 0.92 | AKR1C3 (0.66) | AKR1C3MAPTIL1RNF2PRSS1 | |
| SCHEMBL29503180 | 0.85 | ALDH1A1 (0.56) | AKR1C3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL26144974 | 0.83 | AKR1C3 (0.59) | AKR1C3MAPTIL1RNF2PRSS1 | |
| SCHEMBL2594743 | 0.82 | CA1 (0.53) | AKR1C3F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL5130887 | 0.80 | AKR1C3 (0.56) | AKR1C3MAPTIL1RNF2PRSS1 | |
| SCHEMBL2048495 | 0.79 | HTR2A (0.59) | AKR1C3MAPTCA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585603-B | Prostaglandin EP4Receptor antagonist compounds | 奈克斯拉制药英国有限公司 | 2024-11-08 | — | — | CN | disclosed |